Indication	Status
BREATHE-1 Follow-up Long-term data (safety and survival) on treatment of Pulmonary Arterial Hypertension (PAH)	Phase IV / Completed / Results presented at ATS, 19 May 2003
BREATHE-2 Combination with intravenous epoprostenol i.v. in patients with severe Primary Pulmonary Arterial Hypertension (PPH) or PAH due to scleroderma	Phase IV / Completed / Results published in 2004
BREATHE-3 Treatment of PAH in pediatric patients alone and in combination with epoprostenol i.v.	Phase IV / Completed / Results published in 2003
BREATHE-4 PAH in HIV/AIDS	Phase IV / Completed / Results presented at ESC, 2 Sep, 2003
BREATHE-5 PAH in Eisenmenger's Syndrome (congenital heart disease)	Phase IV / Completed / Results presented at CHEST, 1 Nov 2005
EARLY Early Symptomatic PAH (Class II)	Phase III / Completed  Results presented at ESC,  03 Sep 2007
FUTURE-1 PAH in children	Phase III / Completed Results presented at ESC, 03 Sep 2007
BENEFIT Chronic Thrombo-Embolic Pulmonary Hypertension	Phase III / Completed Results presented at ESC, 03 Sep 2007
ASSET-1/ -2 PAH in Sickle Cell Disease	Phase III / Results expected 2008
COMPASS-1 Combination bosentan and sildenafil in PAH	Phase III / Completed Results presented at ESC, 03 Sep 2007
COMPASS-2 Combination bosentan and sildenafil in PAH	Phase III