The Scientific Advisory Board has the function to review the company's progress in research and clinical development as well as to evaluate new scientific perspectives alongside the company's management.

Ménard, Joël

is Professor of Public Health in Paris, France and a hypertension specialist. He has contributed to the elucidation of the fundamental role of the renin-angiotensin system, which helped to discover and develop breakthrough drugs such as ACE inhibitors and angiotensin-2 blockers. He is the former Head of Clinical Development at Ciba-Geigy, Basel, Switzerland, and the former Chief Medical Officer of Ciba-Geigy France.  

Pratt, Craig

is a Professor of Medicine and Cardiology at the Baylor College of Medicine in Houston, Texas/USA. He has been the principal investigator of a number of large, international drug development programs that have established the role of several currently available drugs used in the treatment of heart failure and arrhythmias. He was Chairman of the FDA's Cardio-Renal Advisory Committee and continues to serve as a consultant to the FDA. He is a member of the development committee for tezosentan. 

Tsien, Richard

is a Professor of Molecular and Cellular Physiology at Stanford University, Palo Alto/USA, and member of the U.S. National Academy of Science and is a leading expert in the field of ion channels. He has elucidated important molecular mechanisms for key biophysical properties of calcium channels and discovered several new ion channels, which have become pharmacological targets.

Kubinyi, Hugo

is Professor of Pharmaceutical Chemistry at the University of Heidelberg and advisor to the Chair of the QSAR and Modelling Society. In addition, he is a member of several scientific advisory boards as well as a member of the editorial boards of a number of scientific journals. From 1987 until his retirement in summer 2001, he headed the Molecular Modelling, X-ray Crystallography and Drug Design group at BASF.

Stewart, Graeme

is Professor of Medicine and Director of both, the Institute for Immunology & Allergy Research and the Department of Clinical Immunology & Allergy at Westmead Hospital in Sydney. His responsibilities as a physician include the care of patients with primary immune deficiency disorders, autoimmune and auto-inflammatory disease. His research is focused on the role of immune function in human disease, in particular control of T-cell function in autoimmune diseases such as multiple sclerosis and has resulted in the publication of over 130 papers in peer-reviewed journals. He also serves on the board of several research organizations.