THE ACTELION ANNUAL REPORT 2004
Shareholder Information
Share price
The following table shows the reported high and low quarterly closing share price of the Actelion shares on the SWX Main Market during the year 2004.
 HighLow
First Quarter156127
Second Quarter150130.75
Third Quarter143.75106.5
Fourth Quarter15398.95
On 31 December 2004 the last reported closing share price was CHF 116.8 and market capitalization of Actelion Ltd was CHF 2.59 billion, compared with a share price of CHF 133.5 and market capitalization of CHF 2.90 billion the previous year. The total number of registered shareholders on 31 December 2004 was 5631.
Listing
Actelion Ltd is organized under Swiss law and is the holding company of the Actelion Group. The company’s initial equity funding was provided in 1998 and 1999 in two separate rounds of financing totaling CHF 66 million.

The registered shares of Actelion Ltd have been listed on the SWX New Market since April 6, 2000 (symbol: ATLN). A total of 1,000,000 primary shares were placed at the company’s Initial Public Offering at the price of CHF 260 per share raising CHF 246.1 million. On June 20, 2001, Actelion Ltd announced a 4:1 split in its shares.
On September 9th, 2002 Actelion listed the company’s registered shares on the SWX Main Market. The SWX Swiss Exchange waived the requirement for a listing prospectus. The trading symbol remains the same and the company will continue to report full quarterly figures.
Investor Relations Calendar 2005
February 24Media/Analyst Conference
April 14Annual General Meeting of Shareholders
April 28Q1 2005 Results
July 28Half Year 2005 Results
October 27Nine months 2005 Results
Board of Directors
Werner Henrich
Chairman, Basilea Pharmaceutica

Fred J. Meyer
Retired Vice Chairman, Omnicom Group

André J. Mueller
Former Chief Financial Officer

Jean-Paul Clozel
Founder, Chief Executive Officer

Robert E. Cawthorn Chairman
Retired Chairman and CEO, Rhône-Poulenc-Rorer

Jean Malo
Chief Investment Officer, Breeco Management L.P.

Armin Kessler
Former Chief Operating Officer, F. Hoffmann-La Roche
Scientific Advisory Board
Joël Ménard
Professor of Public Health, University Pierre et Marie Curie, Paris

Donald Hilvert
Professor of Chemistry at the Swiss Federal Institute of Technology (ETH), Zürich

Richard Tsien
Professor of the Department of Molecular and Cellular Physiology, Stanford University, Palo Alto

Craig Pratt
Professor of Medicine and Cardiology, Baylor College of Medicine, Houston
Business Executive Board
Jean-Paul Clozel
Founder, Chief Executive Officer

Simon Buckingham
President, Head of US, Canada, Asia Pacific

Isaac Kobrin
Senior Vice President, Head of Clinical Development

Andrew J. Oakley
Vice President, Chief Financial Officer

Christian Chavy
President, Head of Europe, Middle East, Latin America

Louis de Lassence
Vice President, Head of Corporate Services

Satoshi Tanaka
President and Representative Director, Japan
Senior Management
Frédéric Bodin
Senior Vice President, Head of International Medical Marketing

Martine Clozel
Senior Vice President, Head of Drug Discovery, Pharmacology & Preclinical Development

Walter Fischli
Founder, Senior Vice President, Head of Drug Discovery, Molecular Biology & Biochemistry