THE ACTELION ANNUAL REPORT 2003
Notes to the financial statements 2003
1. Accounting principles
The financial statements of Actelion Ltd have been prepared in accordance with the accounting principles as prescribed by Swiss Company Law.
2. Material investments
Company

Country

Location

Ownership InterestConsolidation methodFunction

Share Capital

Actelion Pharmaceuticals Australia Pty LtdAustraliaSydney100%FullSalesAUD 2,016,667
Actelion Pharmaceuticals Austria GmbHAustriaVienna100%FullSalesEUR 35,000
Actelion Pharmaceuticals do Brasil LtdaBrazilRio de Janeiro100%FullSalesBRL 376,444
Actelion Pharmaceuticals Canada IncCanadaLaval100%FullSalesCAD 2,600,000
Actelion Pharmaceuticals France SASFranceParis100%FullSalesEUR 500,000
Actelion Pharmaceuticals Deutschland GmbHGermanyFreiburg100%FullSalesEUR 4,500,000
Actelion Pharmaceuticals Hellas SAGreeceChalandri100%FullSalesEUR 421,500
Actelion Pharmaceuticals Italia S r lItalyMilan100%FullSalesEUR 2,015,000
Actelion Pharmaceuticals Japan LtdJapanTokyo100%FullSales, Development JPY 95,000,000
Actelion Pharmaceuticals Nederland BVNetherlandsWoerden100%FullSalesEUR 50,000
Actelion Pharmaceuticals Espana SLSpainBarcelona100%FullSalesEUR 127,100
Actelion Pharmaceuticals Sverige ABSwedenDanderyd100%FullSalesSEK 1,000,000
Actelion Pharmaceuticals Ltd (CH)SwitzerlandAllschwil100%FullResearch,
Marketing,
Development,
Sales,
Production
CHF 614,610
Actelion Pharmaceuticals UK LtdUnited KingdomLondon100%FullSalesGBP 250,000
Actelion Registration LtdUnited KingdomLondon100%FullHolder marketing authorization EUGBP 0
Actelion Pharmaceuticals US IncUnited StatesSouth San Francisco100%FullSalesUSD 5,000
Hesperion Ltd SwitzerlandAllschwil 69.1%FullClinical ResearchCHF 140,000
Actelion Paris Organisation SASFranceParis100%FullMarketingEUR 200,000
Actelion Clinical Operations, Inc.United StatesCherry Hill, New Jersey100%FullClinical ResearchUSD 1,000
Actelion Finance SCALuxembourgLuxembourg100%FullFinancingEUR 31,000
Axovan LtdSwitzerlandAllschwil100%FullResearchCHF 2,271,750
3. Share Capital
At December 31, 2003, the issued share capital amounts to CHF 54,377,870 consisting of 21,751,148 common shares (including 13,500 treasury shares) with a nominal value of CHF 2.50 each. The shares are registered and fully paid-up. Each share is entitled to one vote.
4. Conditional Capital
Since inception the Company has created conditional capital for the establishment of stock option plans, convertible bonds as well as for the potential issuance of shares in relation with certain credit facilities. At December 31, 2003 the Company has conditional capital of CHF 11.9 million.

Movements in conditional capital are as follows:
(in CHF thousands) 
January 1, 20029,434
Creation of conditional capital for Employee Stock Option Plans1,250
Creation of conditional capital for convertible bonds/loans2,120
Exercise of options(604)
December 31, 200212,200
Creation of conditional capital for Employee Stock Option Plans625
Exercise of options(937)
December 31, 200311,888
5. Authorized Capital
The Annual General Meeting of April 23, 2003 authorized the company to create share capital to be used for strategic purposes. The Board of Directors is authorized to increase until April 23, 2005 the share capital by an amount of not more than CHF 10,000,000 by issuance of not more than CHF 4,000,000 fully paid-in registered shares with a nominal value of CHF 2.50 per share.
6. Treasury Shares
During 2003 the Group had no transactions in treasury shares. At December 31, 2003 the Group had 13,500 shares with an average purchase price of CHF 75.41.
7. Guarantees
On December 5, 2003 Actelion Ltd has issued a first demand guarantee of up to EUR 1,100,000 to Deutsche Bank for their credit facility with Actelion Pharmaceuticals Germany GmbH.
In October 2003, Actelion Finance SCA issued a CHF 143.8 million convertible bond (the “Bond“). Under the guarantee agreement signed on October 15, 2003, Actelion Ltd unconditionally guarantees the due payment of the amounts payable by Actelion Finance SCA pursuant to the terms of the Bond, or, upon conversion of the bonds, the due delivery of the shares and/or cash payment for fractions.
8. Significant Shareholders
According to the information available to the Board of Directors the following shareholders held a significant percentage of shares:
Name20032002
 Percentage of share capitalPercentage of voting rightsPercentage of share capitalPercentage of voting rights
Management and Directors***11.8**11.8**14.2**14.2
Rudolf Maag6.76.76.66.6
Deutsche Bank AG Nominees***–***–5.05.0
Chase Nominees Ltd9.65.08.45.0
OrbiMed Advisors***–***–8.55.0
Biotech Invest SA8.78.75.25.2
Fidelity Management & Research Co. 7.45.0***–***–
Fidelitiy International Ltd7.55.0***–***–
 
* No individual has a holding exceeding 5%
** Total excluding Rudolf Maag
*** Percentage below 5%
9. Proposed Appropriation of Available Earnings
 20032002
Retained earnings at beginning of the year(3,171)(1,881)
Net income / (loss) for the year6,765 (1,290)
Total available earnings carried forward3,594 (3,171)
Balance to be carried forward3,594 (3,171)